Monash IVF is a leader in the field of assisted reproduction and is actively involved in several important research projects to ensure continued improvement of procedures and success rates.
Study on embryo implantation
Monash IVF in Melbourne is working in collaboration with Prince Henry's Institute of Medical Research to study the changes that occur in the lining of the uterus (endometrium) at the time of implantation. Embryo implantation is a crucial aspect of normal fertility.
These changes in the lining may not occur in some infertile women. By understanding these differences in endometrial receptivity, a diagnostic test to screen women for problems with embryo implantation could be developed. Biochemical markers for endometrial receptivity could also be used to assist the IVF clinician in deciding the optimal time for embryo transfer.
For this study we are inviting women who are going through an IVF cycle, women who are donating their eggs and fertile women who have had children, to participate. Two samples are taken at the time of egg collection including a uterine wash and a small biopsy of endometrial tissue.
Since the project started in August 2006, well over one hundred and thirty people have participated. The samples collected are now starting to be analysed using an exciting new technology called proteomics. The proteomics system can compare 2,500 different proteins and show which ones are more or less abundant in each group. The first runs have produced some really interesting results and further work is underway. A short paper about the initial results has been submitted to this years Fertility Society Australia (FSA) conference in September. A full publication should follow before the end of the year.
If you would like to know more about the study please contact Caroline Motteram on 03 9429 9188.